Solving the
Quercetin
Quandary
A new form of a stabilised
Quercetin-3O-Glycoside offering
formulation versatility
and improved bioavailability
What Is Quercetin and Why Is It Beneficial?
Quercetin is one of the most abundant bioflavonoids and is frequently found in:
Fruits
Vegetables
Wine
Green Tea
Leaves
-
Quercetin, an active antioxidant, scavenges unstable free radical particles in the body that damage cell membranes, tamper with DNA, and even cause cellular death'
-
Antioxidants can neutralize free radicals, reducing or helping to prevent some of the cellular damage free radicals cause
-
Quercetin is recognized as an immune-supporting ingredient that delivers whole-body benefits'
$261.12
MILLION
Quercetin in the Market
$406.58
MILLION
Growing at a CAGR of 6:53% from 2021 to 20273
The Challenge: Absorption Quandary
Supplemental forms of quercetin are generally challenged with poor solubility-which also causes very low bioavailability, making it ineffective as a dietary supplement.
Quercetin's poor bioavailability is based on not being well absorbed over the intestinal mucosa
To overcome this obstacle quercetin needs to be modified -
natural quercetin derivatives with better solubility and bioavailability needs to be sought out
Brands and consumers alike may be disappointed by ineffective results from conventional quercetin formulations, thereby inhibiting repurchase
The solution: Querceton-3O-Glycoside (Isoquercetin) A natural Quercetin Precursor
A solution to address bioavailability and
water-solubility is NEW SunActive® IsoQ
What is SunActive® IsoQ?
SunActive® IsoQ is a novel delivery system that delivers Isoquercetin which is actively converted to quercetin in the body.
SunActive® IsoQ
vs.
Quercetin
This solubilized form
of quercetin is
25X MORE
bioavailable than
quercetin itself
This high bioavailability is achieved through an encapsulated matrix that makes it completely water soluble, allowing it to reach the gut where it is converted to quercetin and absorbed by the gut lining
What Makes SunActive® IsoQ More Bioavailable?
The glucoside precursor allows IsoQ to be more highly bioavailable than other quercetin and quercetin-derived products.
The sugar molecule in SunActive® IsoQ Isoquercetin is easily cleaved off by enzymes naturally occurring in the gut. Once cleaved and converted to quercetin in the gut, IsoQ can be absorbed and used by the body for its many health benefits.
Isoquercetin
Aglycone
Glucose
Aglycone
Glucose
Aglycone
Enzyme
Improved Solubility Means Versatile
Formulation and Increased Bioavailability!
-
Free quercetin's solubility and bioavailability have long been obstacles for formulators
-
Most quercetin products are not water-soluble because quercetin itself is not soluble, which affects bioavailability
SunActive® IsoQ (Isoquercetin) is derived from rutin which is extracted from the dried flower buds of the Japanese Pagoda ree using a solvent-free, enzymatic process.
The Isoquercetin is encapsulated in an almost cylinder-shaped structure, the result is a water-soluble dietary ingredient
Encapsulating the Isoquercetin is what allows it to solubilize, pass through the stomach unaltered, and reach the gut, where it is then converted to quercetin and absorbed
Improving the bioavailability of quercetin is a highly sought-after benefit to brands formulating high-quality quercetin products that deliver the effective results that consumers demand.
SunActive® IsoQ
25x more bioavailable
than quercetin and it contains the equivalent of at least 11% quercetin, which means that 100 mg of SunActive IsoQ delivers an equivalent of 275 mg of quercetin in the body!
Whole Body Benefits of Quercetin
Quercetin has been extensively studied for immune support, healthy anti-inflammatory e ects, allergy symptom relief, cardiovascular health, exercise performance and muscle function.
Immune Support
Helps improve healthy anti-inflammatory and immune responses (4).
Allergy Relief
Quercetin is an inhibitor of histamine release in humans, the signaling molecule responsible for allergic reactions that cause symptoms like sneezing, watery eyes and sinus congestions (5).
Cardiovascular Health
Quercetin leads to an enhancement in cardioprotective effects (6).
Exercise Performance & Muscle Health C)
Studies demonstrate that quercetin helps with performance and fatigue both with continued and acute consumption before exercising (7,8,9).
Formulating with SunActive® IsoQ
SunActive® IsoQ is:
A yellow, odorless powder, quickly and completely soluble in water
Versatile-a highly bioavailable precursor to quercetin and is suitable for both dry and liquid dietary dietary supplements.
A highly bioavailable and fully soluble replacement for standard quercetin to lower dose size in all formulas; ideal for multi-ingredient formulas, and formulations requiring soluble ingredients.
Smaller Dose
Replace a standard 500 - 1,000 mg dose of regular quercetin with just 180 - 360 mg of SunActive® IsoQ!
ANTIOXIDANT
CARDIO
VASCULAR
HEALTH
CELLULAR
HEALTH
IMMUNE
HEALTH
ALLERGENS
GRAS
VEGAN
INGREDIENT
These statements have not been evaluated by the European Food Safety Agency (EFSA)
These statements are based on facts from scientific and clinical studies and just an information for nutritional experts not for consumers.
These statements are not intended to be used as Health Claims because none of these statements has been approved yet as official Health Claim.
This product is not intended to diagnose, treat or prevent any disease.
Learn More about SunActive® IsoQ
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GET THE WEBSITE
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SunActive® is part of an exclusive portfolio of proprietary ingredients and a trademark of Taiyo.
References
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https://www.mourtsinadorg/health-library/supplement/quercetin
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SaochamP.LoftssonT.y-Cyelodextrin.Ine/Pharm.2017/an101516(1-2):278-292.80i:10.1016/.ijpharm.2016.10.062
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hreps://brandessencereseurch com/pharmaceuticavovercerin-murker
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Mick J.Jurikovo T. Skrovankova S. Sochor J. Quercetin and les Anti-Allargie Immune Response. Molecules. 2016 MUy 1221 (S):623 doi: 10. 35g a/molecules:1050623.
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8001s AW. Haenen GR. Bust A. Heulth cHeets of quercetin: from ansioxidant to nursaccurical. Eur ) Pharacol. 2000 M34 130585(2-3):325-37.d0i:10.1016V -ejphar.2008.03.008.
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SKSHAbeRO.1A Zupane:s. 0.S. Popor. O.0. Tarasenko, AS. Stalamsy, Chapter 27 - Effrets of Quercetin and Its Combinations on Health, Editor (S): Ronald Ross Watson, Victor R. Preedy, Sherma
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Zibadi, Polyphanols: Mechanisms of Action in Human Health and Disease (Srcond Edition). Academic Press, 2018, Pages 373-394, IS8N 9780128130063, doi: 10.1016/B978-0-12-813006-3.00027-1.
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httos://onlinelituary.wiler.com/tovabs/10.1046//-1525-1373-1999.d01-145x
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https:/Fjournals/humanicineties.com/vie/journals/ijsnem/18/a/article-psos.ml
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httos://ww.rrdpi.com/2072-5843/12/0/2850
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