MORINGA SEED
EXTRACT FOR BACK
RELIEF & FATIGUE
A clinically studied ingredient
that addresses the common
causes of discomfort
Back Discomfort & Fatigue Are More Prevalent Than You Think!
A staggeringly common problem
8 out of 10
Adults are estimated to experience back pain at some point in their life
Nearly 65 million
Europeans reported a recent episode of back pain
16 million - 8%
Adults experience persistent or chronic back pain, limiting certain everyday activities (1)
Respondents report that back pain affects everyday activities (2)
Daily Tasks
Exercise
Sleep
Back Pain Complaints Rise Amid Lifestyle Changes Due To The Pandemic
experienced
chronic back pain
pre-Covid-19
experienced
back pain since
Covid-19 (3)
Extreme fatigue can cause injury affecting productivity
A study in the Journal of Occupational
and Environmental Medicine found that
US businesses
lose > $100 billion per year to
fatigue-related absenteeism
and reduced productivity.
13%
of workplace injuries are due to workplace fatigue
Common solutions for back relief are
limited and not sustainable long term
Most common treatments for back discomfort may be potentially harmful, permanently life-altering, expensive or inaccessible.
Dietary supplement back discomfort formulas often include vitamins, minerals and antioxidants that suggest back relief but have not been tested or clinically studied to actually aid back discomfort – until now.
What is MorActive ?
®
Known as a superfood, moringa has been used both in traditional Indian Ayurvedic medicine and as a source of nutrition.
The seeds have been found to have high levels of glucomoringin – this sulfur-containing compound has been found to possess anti-inflammatory, antioxidant and antibacterial properties.
MorActive® is a new, patented, water
extracted ingredient from the moringa seed
Why MorActive® is an Ideal Solution for Back Discomfort & Fatigue
It is a naturally derived, effective option that will appeal to brands and
consumers alike.
The Glucomoringin in MorActive® has been shown to exhibit strong
antioxidant and anti-inflammatory properties.
MorActive® has been shown in a clinical study to be effective in reducing
the severity of lower back discomfort and fatigue (4).
The Proof is in the Science
MorActive® has been studied in a randomized double-blind placebo-controlled clinical study (5)
Methodology and observations
The severity of physical discomfort and fatigue were evaluated by validated scoring scales
Significant changes in lower back discomfort scores were observed after 2 weeks
Changes in fatigue scores were significant after 4 weeks
There was a greater effect in those participants with more severe symptoms
How does it work?
Multiple mechanisms of action for moringin on pain through various biochemical pathways have been proposed by scientists. These include:
-
Antioxidant and anti-inflammatory activity that decreases cellular stress impact fatigue and pain.
-
Desensitization of the TRPA1 ion channel to reduce pain sensations.
-
Activation of PPAR beta/delta nuclear receptor to increase muscle endurance
Moringin is shown to be a very effective and potent agonist of TRPA1 – this ion channel is a known sensor for pain.
Back Discomfort:
-
Glucomoringin in MorActive® is an agonist of the TRPA1 receptor
-
Taiyo GmbH activates TRPA1
-
Desensitizes the associated nerves to future stimuli that may come through the receptor
-
-
When pain stimulus reaches the TRPA1 receptor after it is desensitized, the nerves are not as reactive, resulting in lower pain sensation
Fatigue:
-
Oxidative stress is one of the main factors leading to fatigue
-
Oxidation inhibits normal cell function, generating inflammation, which then leads to fatigue and physical discomfort
-
-
MorActive® acts as an antioxidant which may help to reduce ROS and contribute to fatigue recovery
Formulating with MorActive®
MorActive® is a fine pale-yellow powder, soluble in water, with little taste. It can be formulated into:
Capsules
Tablets
Powders
Gummies
Foods
Beverages
Clean labeling at a Low Dose:
MorActive® is a naturally derived ingredient that delivers benefits at a low dose making it optimal for product formulation.
MorActive® is an excellent option for brands looking to offer new, differentiated products that deliver effective natural solutions for back discomfort and fatigue, helping consumers live the active lifestyle they desire.
Reduce Back
Discomfort
Reduce Fatigue
Antioxidant
Gluten free
Non-GMO
Vegan
These statements have not been evaluated by the European Food Safety Agency (EFSA)
These statements are based on facts from scientific and clinical studies and just an information for nutritional experts not for consumers.
These statements are not intended to be used as Health Claims because none of these statements has been approved yet as official Health Claim.
This product is not intended to diagnose, treat or prevent any disease.
Learn More about MorActive®
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MorActive® is part of an exclusive portfolio of proprietary ingredients and a registered trademark of Taiyo Kagaku.
References
-
Georgetown University Health Policy Institute
-
The American Physical Therapy Association (APTA) Move Forward survey, 2,600 respondents
-
Grech S., Borg J.N., et. al., Back pain: An aftermath of Covid-19 pandemic? A Malta perspective, Musculoskeletal Care. 2021 Jun 6;10.1002/msc.1574. doi: 10.1002/msc.1574. https://pubmed.ncbi.nlm.nih.gov/34092018/
-
Shimizu K., Abe A. et. al. "Impact of Moringa Seed Extract on Daily Fatigue and Low Back Pain," Nutrition Division, Taiyo Kagaku Co., Ltd. 1-3 Takaramachi, Yokkaichi, Mie 510-0844, Japan. doi 2019; 56: 606-613. https://www.shinryo-to-shinyaku.com/db/pdf/sin_0056_08_0606.pdf
-
Ibid.
© Taiyo GmbH